Nonpolar Substances Are Insoluble in Water Ionic and Polar Substances Dissolve in Water Box 2.2 Blood Plasma and Seawaterī. Hydrogen Bonding in Water Box 2.1 Extreme Thermophiles The Cytoskeleton 1.9ġ.10 Biochemistry Is Multidisciplinary 26 Appendix: The Special Terminology of Biochemistry Selected Readings The Endoplasmic Reticulum and Golgi Apparatus C. Gibbs Free Energy and Reaction Rates 1.5Įukaryotic Cells: Structural Features A. Equilibrium Constants and Standard Gibbs Free Energy Changes D. Many Important Macromolecules Are Polymers A. Metabolism and Bioenergetics 10 Introduction to Metabolism 294 11 Glycolysis 325 12 Gluconeogenesis, the Pentose Phosphate Pathway, and Glycogen MetabolismĮlectron Transport and ATP Synthesis PhotosynthesisĪmino Acid Metabolism Nucleotide MetabolismĭNA Replication, Repair, and Recombination Transcription and RNA Processing Protein Synthesis Proteins: Three-Dimensional Structure and Function Introduction 1 Introduction to Biochemistry 2 Water 28Īmino Acids and the Primary Structures of Proteins Science should be as simple as possible, but not simpler. Library of Congress Cataloging-in-Publication Data Principles of biochemistry / H. Where those designations appear in this book, and the publisher was aware of a trademark claim, the designations have been printed in initial caps or all caps. Many of the designations used by manufacturers and sellers to distinguish their products are claimed as trademarks. For information regarding permissions, call (847) 486-2635. To obtain permission(s) to use material from this work, please submit a written request to Pearson Education, Inc., Permissions Department, 1900 E. This publication is protected by Copyright and permission should be obtained from the publisher prior to any prohibited reproduction, storage in a retrieval system, or transmission in any form or by any means, electronic, mechanical, photocopying, recording, or likewise. Manufactured in the United States of America. Copyright ©2012, 2006, 2002, 1996 Pearson Education, Inc., All rights reserved. Cover Illustration: Quade Paul, Echo Medical Media Cover Image Credit: Monkey adapted from Simone van den Berg/Shutterstock Credits and acknowledgments borrowed from other sources and reproduced, with permission, in this textbook appear on page 767. Cheselka Project Manager, Science: Wendy Perez Senior Technical Art Specialist: Connie Long Art Studios: Mark Landis Illustrations /Jonathan Parrish /2064 Design-Greg Gambino Image Resource Manager: Maya Melenchuk Photo Researcher: Eric Schrader Art Manager: Marilyn Perry Interior/Cover Designer: Tamara Newnam Media Project Manager: Shannon Kong Senior Manufacturing and Operations Manager: Nick Sklitsis Operations Specialist: Maura Zaldivar Composition/Full Service: Nesbitt Graphics, Inc. Robert Horton North Carolina State Universityīoston Columbus Indianapolis New York San Francisco Upper Saddle River Amsterdam Cape Town Dubai London Madrid Milan Munich Paris Montreál Toronto Delhi Mexico City Sao Pauló Sydney Hong Kong Seoul Singapore Taipei TokyoĮditor in Chief: Adam Jaworski Executive Editor: Jeanne Zalesky Marketing Manager: Erin Gardner Project Editor: Jennifer Hart Associate Editor: Jessica Neumann Editorial Assistant: Lisa Tarabokjia Marketing Assistant: Nicola Houston Vice President, Executive Director of Development: Carol Truehart Developmental Editor: Michael Sypes Managing Editor, Chemistry and Geosciences: Gina M.
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